The emerging application of cold plasma in healthcare industry

Second session on ‘The emerging application of cold plasma in healthcare industry’ held on 02nd July 2018 at Journal Club Meeting. Biomedical plasma applications in dentistry include dental implant surface, enhancing of adhesive qualities and polymerization, surface coating and plasma cleaning. It is also used for microbicidal activities including decontamination, root canal disinfection and tooth bleaching. Various plasma devices developed for non-thermal atmospheric pressure plasma generation e.g. radio frequency plasma needles, direct current plasma brushes and plasma jets. Plasma oncology uses the cold atmospheric plasma (CAP) for tumor treatment. Several in vivo and in vitro studies presented CAP efficacy in reducing and halting tumor cell growth in low concentration. CAP is also capable of inducing cell death at higher concentration. CAP is found to be more effective than standard treatment against tumor. Dielectric barrier discharge and plasma jet showed significant anticancer capacity over several cell lines. Cold plasma offers chemical free and eco-friendly, non-thermal disinfection and surface modification technology. Plasma treated water is known as plasma activated water (PAW) creates an acidic environment by changing redox potential and conductivity, and generation of reactive oxygen and nitrogen species i.e. ROS and RNS. Comparatively to water, PAW has a different chemical composition and thus can serve as an alternative to microbial disinfection. Several studies have shown synergistic effect of PAW as disinfecting food, promoting seed germination, and plant growth. PAW present potential to increase crop yield especially in drought stress environment.
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